Having reached such a point that it cannot reasonably be overcome.
The expressions ¡Es el colmo! or es la gota que colmó el vaso They are used to describe an event that put an end to your patience, with a relationship, with a specific situation… (After many bad things, my boss wanted to send me to another city, and that was the last straw, that’s why I quit my job). But there are also funny phrases that use the last straw, like the following, to make exaggerated jokes. Enjoy them.